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诱导加同步放化疗治疗中晚期食管癌临床观察 被引量:1

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摘要 目的观察诱导加同步放化疗治疗中晚期食管癌的近期疗效及毒副反应。方法32例中晚期食管癌先采用静脉化疗2周期,后给予局部放射治疗,同时化疗2周期。静脉化疗采用LFP方案:顺铂(DDP)15mg·m-2·d-1,第1 ̄5天;亚叶酸钙(LV)70mg·m-2·d-1,第1 ̄5天;5-氟尿嘧啶(5-Fu)500mg·m-2·d-1,第1 ̄5天;21d为1周期。放疗采用外照射,2Gy/次,5次/周,总照射剂量为60 ̄70Gy。结果近期总有效率为87.5%,毒副反应主要表现为消化道反应及骨髓抑制,常见Ⅱ ̄Ⅲ度白细胞减少。结论诱导加同步放化疗治疗中晚期食管癌,疗效好,毒副反应小,患者可以耐受。
出处 《肿瘤研究与临床》 CAS 2006年第11期768-769,共2页 Cancer Research and Clinic
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