期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

炭疽杆菌毒素致病机制及炭疽疫苗的研究进展 被引量：4

下载PDF
导出
摘要 炭疽毒素是炭疽杆菌的主要致病因子之一。本文对炭疽毒素,尤其是致死毒素的致病机制以及疫苗的研究进展作一综述,并讨论了炭疽的治疗及炭疽毒素在肿瘤治疗中的应用。
作者 熊小培 杨晓明
机构地区 武汉生物制品研究所菌苗研究室
出处 《中国生物制品学杂志》 CAS CSCD 2006年第6期653-656,共4页 Chinese Journal of Biologicals
关键词 炭疽毒素 保护性抗原 致死因子 致死毒素 炭疽疫苗
分类号 R517.201 [医药卫生—内科学]
  • 相关文献

参考文献32

  • 1Chaudry GJ,Moayeri M,Liu SH,et al.Quickening the pace of anthrax research:three advances point towards possible therapies.Trends in Microbiol,2002,10(2):58-62.
  • 2Cunningham K,Mogridge J,Collier RJ,et al.Mapping the lethal factor and edema factor binding sites on oligomeric anthrax protective antigen.Proc Natl Acad Sci USA,2002,99(10):7049-7053.
  • 3Mourez M,Lacy DB,Cunningham K,et al.2001:a year of major advances in anthrax toxin research.Trends in Microbiol,2002,10 (6):287-293.
  • 4Mogridge J,Mourez M,Collier RJ,et al.Involvement of domain 3 in oligomerization by the protective antigen moiety of anthrax toxin.J Bacteriol,2001,183(6):2111-2116.
  • 5Khanna H,Chopra AP,Arora N,et al.Role of residues constituting the 2β1 strand of domain Ⅱ in the biological activity of anthrax protective antigen.FEMS Microbiol Lett,2001,199(1):27-31.
  • 6Batra S,Gupta P,Chauhan V,et al.Trp 346 and Leu 352 residues in protective antigen are required for the expression of anthax lethal toxin activity.Biochem Biophys Res Commun,2001,281 (1):186-192.
  • 7Ascenzi P,Visca P,Ippolito G,et al.Anthrax toxin:a tripartite lethal combination.Fed Eur Biochem Soci Lett,2002,531 (3):384-388.
  • 8Hanna PC,Kruskal BA,Ezekowitz RA,et al.Role of macrophage oxidative burst in the action of anthrax lethal toxin.Mol Med,1994,1 (1):7-18.
  • 9Pannifer AD,Wong TY,Schwarzenbacher R,et al.Crystal structure of the anthrax lethal factor.Nature,2001,414 (6860):229-233.
  • 10Drum CL,Yan SZ,Bard J,et al.Structural basis for the activation of anthrax adenylyl cyclase exotoxin by calmodulin.Nature,2002,415(6870):396-402.

二级参考文献9

  • 1[1]Swanson-Biearman B,Krenzelok EP.Delayed life-threatening reaction to anthrax vaccine.J Toxicol Ciln Toxicol,2001,39(1):81-84
  • 2[2]Demicheli V,Rivetti D,Deeks JJ et al.The effectiveness and safety of vaccines against human anthrax:a systematic review.Vaccine,1998,16(9-10):880-884
  • 3[3]Baillie L.The development of new vaccines against Bacillus anthracis.J Appl Microbiol,2001,91:609-613
  • 4[4]Leppla SH.Development of an improved vaccine for anthrax.J Clin Invest,2002,110(2):141-144
  • 5[5]Enserink M,Marshall Eliot.New anthrax vaccine gets a green light.Science,2002,296:639-640
  • 6[6]Singh Y,Leppla SH,Bhatnagar R et al.Internalization and processing of lethal toxin by toxin-sensitive and-resistant cells.J Biol Chem,1989,264(19):11099-11102
  • 7[7]Kobiler D,Gozes Y,Rosenberg H et al.Efficiency of protection of guinea pigs against infection with Bacillus anthracis spores by passive immunization.Infect Immun,2002,70(2):544-550
  • 8[8]Ivins BE,Pitt ML,Fellows PF et al.Comparative efficacy of experimental anthrax vaccine candidates against inhalation anthrax in rhesus macaques.Vaccine,1998,16:1141-1148
  • 9[9]Singh Y,Ivins BE,Leppla SH et al.Study of immunization against anthrax with the purified recombinant protective antigen of Bacillus anthracis.Infect Immun,1998,66:3447-3448

共引文献14

同被引文献26

  • 1展德文,王芃,王令春,张兆山.炭疽芽胞杆菌疫苗研究进展[J].微生物学报,2005,45(1):149-152. 被引量：4
  • 2黄毓茂,黄引贤,余志东,李乃津.2型猪链球菌病的初步研究[J].中国畜禽传染病,1993,15(5):1-3. 被引量：54
  • 3王建,刘佩红,沈素芳,沈莉萍,王永康,陆承平.马链球菌兽疫亚种类M蛋白亚单位疫苗小鼠免疫试验[J].中国兽医学报,2006,26(5):495-497. 被引量：3
  • 4卫生部卫生监督中心标准处．传染病诊断标准及相关法规汇编．北京：中国标准出版社，2003：100—110．
  • 5中国标准出版社第一编辑室编.动物防疫标准汇编.北京:中国标准出版社,2004:724-740.
  • 6王季午.传染病学.3版.上海:上海科学技术出版社,1998:516-517.
  • 7默里PR(美),徐建国,主译.临床微生物学手册.北京:科学出版社,2005:495.
  • 8Anderson PD, Bokor G. Bioterrorism:pathogens as weapons [J]. J Pharm Pract,2012,25(5) :521-529.
  • 9Tournier JN ,Ulrich RG, Quesnel-Hellmann A, et al. An- thrax,toxins and vaccines: a 125-year journey targeting Bacillus anthracis[J]. Expert Rev Anti Infect Ther, 2009,7 (2) : 219-236.
  • 10Beierlein JM,Anderson AC. New developments in vac- cines,inhibitors of anthrax toxins,and antibiotic thera- peutics for Bacillus anthracis[J]. Curt Med Chem, 2011,18(33) :5083.

引证文献4

二级引证文献6

中国生物制品学杂志
2006年 第6期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部