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应重视实验室检查在慢性肾病早期诊断中的应用 被引量：78

Emphasis on the utility of laboratory examination on early diagnosis of chronic kidney disease
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摘要 慢性肾病(CKD)是世界范围内的公共健康问题,其发病率呈迅速增长趋势。实验室检查是早期发现CKD的重要手段。早期诊断,以便及时采取有效的措施在延缓肾病向肾功能衰竭的进展中具有重要意义。我们在充分认识CKD的基础上,应正确开展其检测工作指导临床应用。 Chronic kidney disease （CKD） has become a pandemic. Laboratory assay takes the important role in early diagnosis of CKD. We should develop these assays correctly on the basis of full understanding of CKD and guide clinical use for them in laboratory medicine.
作者 徐国宾 李志艳
机构地区 北京大学第一医院检验科
出处 《中华检验医学杂志》 CAS CSCD 北大核心 2006年第11期961-965,共5页 Chinese Journal of Laboratory Medicine
关键词 慢性肾病 肾小球滤过率 白蛋白尿 Nephrosis Glomerular filtration rate Albuminuria
分类号 R692 [医药卫生—泌尿科学]
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参考文献18

  • 1Garg AX, Kiberd BA, Clark WF, et al. Albuminuria and renal insufficiency prevalence guides population screening: results from the NHANES Ⅲ.Kidney Int,2002,61:2165-2175.
  • 2Ramirez SP, Mcclellan W, Port FK, et al. Risk factors for proteinuria in a large, multiracial, southeast Asian population. J Am Soc Nephrol, 2002,13 : 1907-1917.
  • 3Coresh J, Astor BC, Greene T, et al. Prevalence of chronic kidney disease and decreased kidney function in the adult US population: Third national health and nutrition examination survey. Am J Kidney Dis,2003,41:1-12.
  • 4Chadban SJ, Briganti EM, Kerr PG, et al. Prevalence of kidney damage in Australian adults: The AusDiab kidney study.J Am Soc Nephrol,2003,14:s131-s138.
  • 5Iseki K, Jseki C, Ikemiya Y, et al. Risk of developing end-stage renal disease in a cohort of mass screening. Kidney Int, 1996,49:800-805.
  • 6Li PK, Kwan BC, Leung CB, et al. Prevalence of silent kidney disease in Hong Kong: The Screening for Hong Kong Asymptomatic Renal Population and Evaluation (SHARE) program. Kidney Int Suppl,2005,94 :s36-40.
  • 7Myers GL, Miller WG, Coresh J, et al. Recommendations for improving serum creatinine measurement : a report from the Laboratory Working Group of the National Kidney Disease Education Program. Clin Chem, 2006,52:5-18.
  • 8李海霞,张春丽,徐国宾,王学晶,李淑葵,李志艳,张旭初,夏铁安.健康人群血清半胱氨酸蛋白酶抑制剂C与肌酐分布及其评价慢性肾脏病患者肾小球滤过功能的比较研究[J].中华检验医学杂志,2006,29(11):970-974. 被引量：179
  • 9Stevens LA, Coresh J, Greene T, et al. Assessing kidney function-measured and estimated glonlerular filtration rate. N Engl J Med ,2006,354:2473-2483.
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二级参考文献12

  • 1Randers E, Erlandsen EJ. Serum cystatin C as an endogenous marker of the renal function-a review. Clin Chem Lab Med, 1999,37:389-395.
  • 2Dharnidharka VR,Kwon C, Stevens G. Serum cystatin C is superior to serum creatinine as a marker of kidney function : a meta-analysis.Am J Kidney Dis,2002,40:221-226.
  • 3National Kidney Foundation. K/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification.Am J Kidney Dis,2002,39(2 Suppl 1 ) :S1-266.
  • 4Levey AS, Bosch JP, Lewis JB, et al. A more accurate method to estimate glomerular filtration rate from serum creatinine : a new prediction equation. Ann Intem Med, 1999,130:461-470.
  • 5Norlund L, Fex G, Lanke J, et al. Reference intervals for the glomerular filtration rate and cell-proliferation markers : serum cystatin C and serum beta2-microglobulin/cystatin C ratio. Scand J Clin Lab Invest, 1997,57:463-470.
  • 6Newman DJ, Thakkar H, Edwards RG, et al. Serum cystatin C measured by automated immunoassay : a more sensitive marker of changes in GFR than serum creatinine. Kidney Int, 1995,47 : 312-318.
  • 7Erlandsen E J, Randers E, Kristensen JH. Reference intervals for serum cystatin C and serum creatinine in adults. Clin Chem Lab Med, 1998,36:393-397.
  • 8Uhlmann E J, Hock KG, Issitt C, et al. Reference intervals for plasma cystatin C in healthy volunteers and renal patients , as measured by the Dade Behring BN Ⅱ System ,and correlation with creatinine. Clin Chem, 2001,47 : 2031-2033.
  • 9Finney H,Newman DJ, Price CP. Adult reference for serum cystatin C,creatinine and predicted creatinine clearance. Ann Clin Biochem,2000,37:49-59.
  • 10Laterza OF,Price CP,Scott MG. Cystatin C :an improved estimator of glomerular filtration rate? Clin Chem ,2002,48:699-707.

共引文献178

同被引文献451

引证文献78

二级引证文献404

中华检验医学杂志
2006年 第11期

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