感染性疾病中血清降钙素原和C反应蛋白检测的临床意义

Determination of Serum Procalcitonin and C-reactive Protein in Infection Diseases

目的:探讨感染性疾病中血清降钙素原(PCT)和C反应蛋白(CRP)的变化及其临床意义。方法:检测100例感染性疾病和40例非感染性疾病血清中PCT、CRP的含量。结果:细菌感染组与病毒感染组、非感染组比较PCT、CRP明显升高,差异有显著性(P<0.01)。病毒感染组与非感染组比较PCT、CRP轻度升高,差异无显著性(P>0.05)。细菌感染组治疗前后PCT、CRP比较差异有显著性(P<0.01)。结论:感染时,PCT、CRP的检测有助于疾病的鉴别诊断,动态检测其变化对疗效判断有一定的价值。

Objective To study the serum proealcitonin （PCT） and C-reactive protein （CRP） in infection diseases and its clinical significance. Methods The contents of PCT and CRP insera of 100 and 40 noninfeeted cases of newborn were examed. Results The levels of PCT and CRP in bacteria infected group were significantly higher than that in virus infected and non-infected groups（P 〈 0.01 ）. The levels of PCT and CRP in virus infected group were slightly hightly higher than that in non-infected group and there was no significicant difference among them（ P 〉 0. 05）. In the bacteria infected group there were significant differences between the pretreament levels of PCT and CRP and post treatment levels of them（P 〈 0.01 ）. Conclusion The examination of serum PCT and CRP is helpful to make distinctive diagnosis for infections at earlystage, and the dynamic determination of their level change is valuable for judgement of therapeutic results.