胃粘膜活检100例癌周间质反应的特点及意义

The Significance of the Pericancerous Fibrous or Fibroblastic Reaction in 100-case Gastric Cancer Biopsies

对病理诊断为胃癌的１００例胃镜活检标本进行观察，结果发现：不同组织学类型的胃癌，其间质反应表现不同．按检出率统计，有纤维组织性反应者，高分化腺癌（６２．５％）高于低分化腺癌（３７．５％），有显著性差异（Ｐ＜０．０５）；有纤维母细胞反应者，粘液细胞癌（５６．７％）、低分化腺癌（２８．３％）和高分化腺癌三者间差异非常显著（Ｐ＜０．０１）．文章就癌周间质反应的辅助性诊断意义进行初步探讨，并认为癌周间质反应可作为癌性浸润的证据。

The gastroscopic biopsies were observed in 100 cases of gastric carcinoma con-firmed pathologically.The results indicated that pericancerous stromal reaction varied with histo-logical types of gastric carcinoma.In accordance with the statistics of detection rate,the percent-age of pericancerous fibrous reaction was higher in well-differentiated adenocarcinoma(62.5%)than in poorly-differentiated adenocarcinoma(37.5%),disclosing a statistical significance(P<0.05).Pericancerous fibroblastic reaction was 56.5% in mucous cell carcinoma,28.3%in poorly-differentiated adenocarcinoma and 13.0% in well-differentia ted adenocarcinoma,re-vealing a statistically significant difference( P<0.01).Briefly discussed was the significance ofadjuvant diagnosis for stromal reaction,which may be regarded as an identification index for can-cerous invasion.