中国软珊瑚化学成分的研究(三十六)——两种神经酰胺的结构测定

STUDIES ON THE CHEMICAL CONSTITUENTS OF THE CHINESE SOFT CORAL ( III X VI ) --Structures of two ceramides

从中国南海甘蓝柔荑软珊瑚(Nephthea brassica Kkenthal)中分离得到2种神经酰胺1和2,通过对它们的光谱数据和元素分析数据的分析,鉴定其结构分别为N-2-(1,3,5-三羟基-十八烷基)-十九酰胺和(E)-N-2-(1,3-二羟基-4-十八烯基)-十六酰胺。

The chemical constituents of the soft coral Nephthea brassica collected from the South China Sea have been studied. Two ceramides 1 and 2 were isolated. The ceramide 1 is a white powder with a formula C37H75NO4, mp 113-114C, and 2 is a white powder with a formula C34H67NO3, mp 89-90C. The structures of 1 and 2 were, respectively, designated as N-2-(1 , 3, 5-tri-hydroxy octadecyl)-nonadecamide and (E)-N-2-(1, 3-dihydroxy octadecan-4-en)-hexadecamide by spectroscopic analysis and elemental analysis. The ceramide 1 was discovered in the nature for the first time.