脱落细胞β_2微球蛋白检测对子宫颈癌的诊断意义

Significance of detection of cervical exfoliatted cell β_2 microglobulin in cervical cancerdiagnosis

对３０例子宫颈癌宫颈脱落细胞β２微球蛋白（β２ｍ）免疫细胞化学标记，寻找β２ｍ丢失的阴性细胞（即肿瘤细胞）。结果，对子宫颈癌均作出正确诊断，无一假阴性；而常规细胞学检查２６例阳性，４例阴性。本文提示，子宫颈脱落细胞β２ｍ检测，有重要的临床价值。

As the cell atypia increases,the cell surface β2 microglobulin(β_2m)becomes lost gradually,β_2m lost exfoliatedcells were detected by PAP method in 30 cervical cancer patients in this work.It was found that β_2m lost exfoliated cellswere detected in 30 cases of cervical cancer patients,and diagnosed as cervical cancer.It is considered that detection ofexfoliated cell β_2m has very high accuracy of cervical cancer diagnosis,can play a important role in cervical cancerdiagnosis.