门静脉阻断兔肝VX2移植瘤的DSA评价

Hepatic VX2 tumor after portal vein occlusion in rabbits:evaluation with DSA

目的评价DSA在兔肝VX2移植瘤经门静脉阻断后显示肝动脉与门静脉的价值。方法20只新西兰大白兔随机分为移植瘤体生长3周后门静脉阻断组和移植瘤体未行门静脉阻断对照组,2周后分别行兔肝动脉与门静脉DSA检查。结果DSA在肝动脉分支的显示效果上较血管灌注好,实验组肝左外叶肿瘤组织可见少许肝动脉供血。肝左外叶门静脉分支结扎(PBL)者均能被DSA证实。结论DSA可直观地显示兔肝动脉与门静脉的空间解剖细节,在兔肝门静脉阻断效果的评价中起着重要作用。

Objective To study the value of DSA for hepatic vascular anatomy, and to evaluate the efficacy of portal vein occlusion in rabbits with hepatic VX2 tumor. Methods Twenty New Zealand white rabbits were randomly divided into two groups with 10 in each group, including test group A and positive control group B of ham operation. For the test group A, portal branch ligation（PBL）was performed for the left external branch after 3 weeks of the tumor implantation to the left external lobe. Two weeks later,the DSA of hepatic artery and portal vein were performed in all of the rabbits. Results The total displaying effectiveness of the branches of hepatic artery by DSA was better than that by vascular perfusion. There was hypovascular blood supply to hepatic artery implantation of the tumor in the test group A, comparing with that of the group B. Conclusion DSA can clearly display spacial details of the hepatic vascular anatomy in rabbits, and play an important role in post-procedual evaluation of the portal vein occlusion in rabbits.