冠状动脉介入治疗时对比剂的选择与应用

Contrast media selection in patients undergoing coronary intervention

对比剂是冠状动脉介入治疗过程中一个必不可少的组成部分,由于接受介入治疗的冠心病患者越来越多,对比剂的安全问题也越来越引起人们的关注。与早期的对比剂相比,新一代的对比剂在冠状动脉介入治疗中的安全性得到了随机临床试验结果的支持,等渗的非离子型对比剂可明显降低冠状动脉血栓性不良事件并发症以及对比剂肾病的发生率,高危患者受益更为明显。

Contrast media is an important ingredient for percutaneous coronary intervention. Because more and more patients with coronary artery disease were revascularizated by this way, cardiologists have become concerned about the safety of contrast media. Compared to previous contrast media. The safety of new generation of contrast agents has been supported by evidences from randomized clinic trials, non ionic and iso-osomolar contrast mediums with low incidence of clotting adverse events and contrast induced-nephropathy, and high risk patients may benefit from new generation of contrast agents more significant.