URC测试对消化道恶性肿瘤根治术后复发监测的临意义

The clinical research on URC test for the relapse after the digestive tract cancer radical operation

目的:探讨癌症尿液筛查监测试剂(URC)测试对消化道恶性肿瘤术后复发监测诊断的临床意义。方法:对100例消化道恶性肿瘤根治术后病人每月一次URC测试,与实际复发情况,进行阳性符合率、阴性符合率、灵敏度、假阳性率统计分析。结果:两家医院2年内100例患者共测480次,阳性146次(30.4%),阴性334例次(69.6%),其中真阳性124次(25.8%),真阴性310次(64.6%),阳性符合率84.9%,阴性符合率92.8%。,灵敏度83.8%,假阳性率(误诊率)6.6%。结论:URC测试对消化道恶性肿瘤根治术后复发监测有临床实用意义,能对复发早诊断提供线索,灵敏度高、误诊率低,无创简便易行,值得临床进一步研究推广。

Objective：To explore the URC test for monitoring the relapses after digestive tract cancer radiacal operation . Methods： Total of 100 Digestive tract cancer patients with radical operation were tested with URC once monthly, to analyse positive coincidence rate negative coincidence rate sensitivity and mistake diagnostic rate. Resuits： There were 480 times totally to 100 pateints tested by URC in two years , the positive case is 146 times （30.4%）, the negative case is 334 times（69.6% ）, true positive 124 times（25.8% ）, true negative 310 times （ 64.6% ）, the positive coincidence rate was 84.9%, the negative coincidence rate 92.8% , sensitivity was 83.8%, false positive rate（ misdiagnosis rate） 6.6%. Conclusion： URC test after radical operation can early provide the clues to relapse of digestive tract cancer,its sensitivity is high, the misdiagnosis rate is low, no wound, simple and easy handling.