期刊文献+

老年心肌梗塞与脂蛋白(a)、血小板活性及凝血功能的关系 被引量:11

Relationships between aged myocardial infarction and lipoprotein(a),platelet activation and coagulation function
下载PDF
导出
摘要 探讨老年心肌梗塞(MI)与脂蛋白(a)[Lp(a)]、血小板活性及凝血功能的关系。方法:选择经冠状动脉造影(CAG)诊断为老年MI患者(n=68)作为老年MI组,选择以胸闷和胸痛等不典型症状来诊、但CAG正常的患者(n=74)作为对照组;同时采集静脉血检测Lp(a)、血小板a颗粒膜蛋白-140(GMP-140)、血浆纤维蛋白原(FG)、血浆纤维蛋白肽A(FPA)、血脂、血糖(FGB)和血小板(Plt)。结果:与对照组比较,老年MI患者LP(a)、GMP-140、FG和FPA均增高(P>0.05);总胆固醇(TC)与低密度脂蛋白(LDL-C)增高(P>0.05);甘油三酯(TG)、高密度脂蛋白(HDL)、FGB及Plt差异无显著性(P>0.05)。结论:老年MI患者与LP(a)、GMP-140、FG和FPA的增高关系密切,TC及LDL-C的增高与老年MI有关。
出处 《吉林大学学报(医学版)》 CAS CSCD 北大核心 2006年第6期1094-1096,共3页 Journal of Jilin University:Medicine Edition
基金 吉林省科技厅重点项目资助课题(200595128)
  • 相关文献

参考文献9

  • 1Rosengren A, Wilhelmsen L, Eriksson E, et al. Lipoprotein(a) and coronary heart disease: a prospective case-control study in a general population sample of middle aged men[J].BMJ, 1990, 301: 1248-1251.
  • 2Kostner GM, Avogaro P, Cazzolato G, et al. Lipoprotein Lp ( a ) and the risk for myocardial infarction[J].Atherosclerosis, 1981, 38: 51-61.
  • 3李牧蔚,高传玉,黄克钧,牛振民,朱中玉,沈玉祥.脂蛋白(a)在心肌梗死冠状动脉血栓形成及再通中的临床价值[J].中华内科杂志,2004,43(2):134-135. 被引量:12
  • 4Angles-Cano E. Structural basis for the pathophysiology of lipoprotein (a) in the atherp-thrombotic process[J]. Braz J Med Biol Res, 1997, 30:1271-1280.
  • 5Scharfstein JS, Abendschein DR, Eisenberg PR, et al.Usefulness of fibrinogenolytic and procoagulant markers during thrombolytic therapy in predicting clinical outcome inacute myocardial in farction. TIMI-5 Investigators.Thrombolysis in myocardial infartion [J].Am J Cardiol,1996, 78: 503-510.
  • 6Lind P, Hedblad B, Stavenow L, et al. Influence of plasma fibrinogen Levels on the incidence of myocardial infarction and death is modified by other inflammation-sensitive proteins: a long-term cohort study[J]. Arterioscler Thromb Vasc Biol,2001, 21: 452-458.
  • 7Eto K, Ochiai M, Isshiki T, et al. Platelet aggregability under shear is enhanced in patients with unstable angina pectoris who developed acute myocardial infarction[J]. Jpn Circ J, 2001, 65: 279-282.
  • 8Smith EB, Keen GA, Grant A, et al, Fate of fibrinogen in human arterial intima [J]. Arteriosclerosis, 1990, 10: 263- 275.
  • 9Goto S, Handa S. Coronary thrombosis. Effects of blood flow on the mechanism of thrombus formation[J]. Jpn Heart J , 1998, 39: 579-596.

二级参考文献5

  • 1Marcovina SM,Koschinsky ML.Lipoprotein ( a) as a risk factor for coronary artery disease[].The American Journal of Cardiology.1998
  • 2Rosengren A,Wilhelmsen L,Eriksson E,et al.Lipoprotein (a) and coronary heart disease: a prospective case-control study in a general population sample of middle aged men[].British Medical Journal.1990
  • 3Kostner GM,,Avogaro P,Cazzolato G,et al.LipoproteinLp(a)and the risk for myocardial infarction[].Atherosclerosis.1981
  • 4Angles-Cano E.Structural basis for the pathophysiology of lipoprotein(a)in the athero-thrombotic process[].Brazilian Journal of Medical and Biological Research.1997
  • 5Moliterno DJ,Lange RA,Meidell RS,et al.Relation of plasma lipoprotein ( a ) to infarct artery patency insurvivors of myocardial infarction[].Circulation.1993

共引文献11

同被引文献75

引证文献11

二级引证文献62

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部