功能化酸性离子液体催化合成氯乙酸异丙酯的研究

Synthesis of isopropyl chloroacetate catalyzed by acidic ionic liquids

研究了功能化酸性离子液体催化合成氯乙酸异丙酯的反应,考察了不同离子液体、反应温度、反应时间和离子液体与反应物物质的量比[n(离子液体)∶n(反应物)]等对反应的影响。结果表明,以离子液体N-(4-磺酸基丁基)吡啶硫酸氢盐{[(CH2)4SO3HPy]HSO4}为催化剂,在60℃、n(离子液体)∶n(反应物)=1∶5,反应4 h后,反应的转化率和选择性分别为91%和100%。催化剂循环使用5次,催化活性不变。

Synthesis of isopropyl chloroacetate catalyzed by acidic ionic liquids （IL） was studied, including influences of different ionic liquids, reaction temperature, reaction time and quantity of ionic liquid （mole ratio of reactant to IL）. Isopropanol conversion of 91% and the selectivity to i^propyl chloroacetate of 100% were attained under optimum reaction condition as follows, n （reactant） ： n （IL）= 5：1, 60 ℃, 4 h. The ionic liquid can be used repeatedly for five times without remarkable loss of catalytic activity.