1Susan C,Louis M,Vivian F.Hyperhomocysteinemia:an emerging and important risk factor for thromboembolic and cardiovascular disease[J].Clin Chem,1996; 106:709-22.
3Sutton TK,Bostom A,Sellub J,et al.High homocysteine levels are independently related to isolated systolic hypertension in order adults[J].Circulation,1997; 96 (16):1745.
4Rutan G.Mortality associated with diastolic hypertension and isolated systolic hypertension among men screened for the Multiple Risk Factor Intervention Triak[J].Circulation,1998 ;77:504.
7Mudd SH,Levy HL.Plasma homocyst(e) ine or homocysteine[J].N Engl J Med,1995 ;333:325.
8Tsikas D,Sandmann J,Rossa S,et al.Investigations of S-transnitrosylation reactions between olw-and high-molecular-weight S-nitrosocom-pounds and their thiols by high-performance liquid chromatography and gas chromatography-mas spectrometry[J].Analbiochem,1999 ;270:231-41.
10Jacob RA,Wu MM,henning SM,et al.Homocysteine increases as folate decreases in plasma of healthy men during short-term dietary folate and methyl group restriction[J].J Nutr,1994; 124:1072 -80.
4Fryer RH,Wilson BD,Gubler DB et al.Homocysteine,a risk factor for premature vascular disease and thrombosis,induces tissue factor activity in endothelial cells[J].Arterioscler and Thromb,1993,13(9):1327-33.
5Khattar RS,Senior R,Swales JD et al.Value of ambulatory intraarterial blood pressure monitoring in the long-term prediction of left ventricular hypertrophy and carotid atherosclerosis in essential hypertension[J].J Hum Hypertens,1999,13(2):111-7.
6Wang H.Pharmacological characteristics of the novel antihypertensive drug,iptakalim hydrochloride,and its molecular mechanisms[J].Drug Dev Res,2003,58(1):65-8.
7Koga T,Claycombe K,Meydani M.Homocysteine increases monocyte and T cell adhesion to human aortic endothelial cells[J].Atherosclerosis,2002,161(2):365-74.
8Sung FL,Siow YL,Wang GP et al.Homocysteine stimulates the expression of monocyte chemoattractant protein1 in endothelial cells leading to enhanced monocyte chemotaxis[J].Mol Cell Biolchem,2001,216(1-2):121-8.
9Silverman MD,Tumuluri RJ,Davis M et al.Homocysteine upregulates vascular cell adhesion molecule-1 expression in cultured human aortic endothelial cells and enhances monocyte adhesion[J].Arterioscler Thromb Vasc Biol,2002,22(4):587-92.
10Fang J,Madhavan S,Cohen H,et al. Isolated diastolic hypertension: A favorable finding among young and middle-aged hypertensive subject [J]. Hypertension, 1995; 26 : 377-382.
4Van CA, Golledge J. Osteoprotegerin, vascular calcification and atherosclerosis [J]. Atherosclerosis, 2009,204 (2) : 321 - 329.
5Shao JS,Sierra OL, Cohen R,et al. Vascular calcification and aortic fibrosis A bifunctional role for osteopontin in diabetic arteriosclerosis [J]. Arteriosclerosis ,Thrombosis, and Vascular Biology,2011,31 (8):1821-1833.
6Callegari A,Coons M,Ricks J,et al. Bone marrow-or vessel wall-derived osteoprotegerin is sufficient to reduce atheroscle- rotic lesion size and vascular calcification [J]. Arterioscle- rosis,Thrombosis,and Vascular Biology, 2013,33 (11 ) : 2491-2500.
7Derwall M,Malhotra R,Lai CS,et al. Inhibition of bone morphogenetic protein signaling reduces vascular calcifi- cation and atheroselerosis [J]. Arteriosclerosis,Thrombosis, and Vascular Biology, 2012,32 (3) : 613-622.
8Renoux C, Dell" Aniello S, Garbe E, et al. Transdermal and oral hormone replacement therapy and the risk of stroke :a nested case-control study [J]. British Medical Journal,2010, 340 : c2519.
9Schierbeck LL,Rejnmark L,Tofteng CL,et al. Effect of hor- mone replacement therapy on cardiovascular events in re- cently postmenopausal women: randomised trial [J]. British Medical Journal, 2012,345 (6409) : 1990-1993.
10Cooney MT,Vartiainen E,Laakitainen T,et al. Elevated rest- ing heart rate is an independent risk factor for cardiovascu- lar disease in healthy men and women [J]. American Heart Journal,2010,159(4) :612-619.
