舒金克喘胶囊制备过程中麻黄、厚朴有效成分追踪

Investigate into of effective constituent transference of Herba Ephedrae and Cortex Magnoliae Officinalis in preparation course of Shujin Kechuan capsule

目的:考察舒金克喘胶囊制备过程中麻黄、厚朴主要有效成分的转移率和保留率。方法:用HPLC法追踪药材、醇提液、25%浓缩液、50%浓缩液、100%浓缩液、成品中盐酸麻黄碱、和厚朴酚、厚朴酚的去向。结果:成品中盐酸麻黄碱、和厚朴酚、厚朴酚的转移率分别为56.32%、14.43%、14.56%。结论:浓缩、干燥工艺应该在减压、低温下进行。

Objective：Investigate into transport rate and retention rate transference of principal effective constituent in Shujin Kechuang capsule ,a new development Chinese patent medicine for theraphy asthma. Method： HPLC was applied to analyze the content of ephedrine hydrochloride and honokiol and magnolol in crude drugs and 60% ethanol extracting solution and 25% concentrated solution,50% concentrated solution, 100% concentrated solution and finished product（ Shujin Kechuang capsule）. Result： he transport rate of ephedrine hydrochloride and honokiol and magnolol is 56. 32%, 14. 43%. 14. 56% in the finished product respectively. Conclusion： should be concentrate and desiccation in the condition that decompress and low temperature.