摘要
针对牛黄解毒片(丸)的安全性问题,通过考证牛黄解毒丸源流和品种演变情况,分析雄黄功效历史的沿革、毒性和用法用量的记载,提出导致牛黄解毒片(丸)及含砷成方制剂的安全性相关因素,并对如何加强该类成方制剂的监督管理提出建议。
By comprehensively reviewing the origin and history of Niuhuang Jiedu Wan and its "derivatives", we studied the clinical records of realgar, investigated its clinical usage, dosage, efficacy, and toxicity in the literatures. We pinpointed the factors that might be associated with safety problems of Niuhuang Jiedu Pian (Wan) and other traditional Chinese medicine (TCM) preparations containing arsenic substances. In this article we also put forward suggestions for strengthening the surveillance and administration of similar TCM preparations.
出处
《中国中药杂志》
CAS
CSCD
北大核心
2006年第23期2010-2013,共4页
China Journal of Chinese Materia Medica
关键词
牛黄解毒片(丸)
砷
雄黄
不良反应
监督管理
Niuhuant
iiedu Pian (Wan)
arsenic
realgar
adverse reaction
surveillance and administration