摘要
目的观察了解盖诺为主化疗方案联合局部放射治疗复发和转移乳腺癌的临床疗效和毒性反应。方法全部病例确诊后均先予NP或NA方案化疗1～2周期后立即予局部放疗，照射野包括所有病灶，DT35—60Gy不等。放疗后再予原方案化疗1～4个周期。结果全部病例均完成全程放疗及至少2周期化疗，其中CR9例，PR11例，有效率76．9％。最主要的毒性反应为白细胞降低，但积极处理后均可耐受。结论以盖诺为主的化疗联合局部放射治疗复发或转移的乳腺癌疗效确切，毒性反应可以耐受。
Objective To investigate the therapeutic effect of chemotherapy based on navelbine combined with local radiotherapy cured recurrence or metastasis of breast carcinoma. Methods All patients were treated with chemotherapy （NP or NA program） for 1 ～ 2 cycles followed with local radiotherapy （DT 35 - 60 Gy, the radiation field included all lesions）. After radiotherapy, chemotherapy （the same program） was used for 1 ～ 4 cycles in every patient. Results All patients were treated at least 2 cycles chemotherapy and local radiotherapy.The response rate was 76.9% （9 patients in CR and 11 patients in PR）. The main toxic reaction was leucocytopenia. It can be cured by active treatment. Conclusions It can obtain a good result by chemotherapy based on navelbine combined with local radiotherapy in recurrence or metastasis of breast carcinoma and the toxic reaction was very low.
出处
《肿瘤基础与临床》
2006年第6期482-483,共2页
journal of basic and clinical oncology
关键词
盖诺
化疗
放疗
乳腺癌
navelbine
chemotherapy
radiotherapy
breast carcinoma
