彩色多普勒超声对肝癌介入治疗后的疗效评价

The Evaluation of Interventional Treatment of Primary Liver Carcinoma by Color Doppler Flow Imaging

目的探讨彩色多普勒超声对原发性肝癌肝动脉栓塞治疗后的疗效评价。方法应用彩色多普勒超声观察32例原发性肝癌介入治疗前后的声像图改变及瘤体内血液动力学变化。结果本组病例均为高血供,介入治疗后瘤体有不同程度缩小,治疗前13例巨块型肝癌大小平均13 cm×12 cm,治疗后平均12 cm×9 cm;6例结节型肝癌术前大小6 cm×5 cm,术后平均4 cm×5 cm;TAE后肿瘤内部动脉血流变化明显,肿瘤血管完全消失11例,明显减少16例,减少5例。治疗前肿瘤内部动脉血流vmax(56±12)cm/s,治疗后肿瘤内部动脉血流vmax(25±12)cm/s,两者相比差异有统计学意义(P<0.05〉,介入后血液中AFP下降。结论彩色多普勒能有效评价肝癌介入治疗疗效。

Objective To evaluate the effectiveness of hepatic arterial embolization （TAE） on primary hepatic cancers by color Doppler flow imaging. Methods Sonographic appearance and hemodynamic changes of 32 cases with primary liver carcinomas were investigated by color Doppler flow imaging before and after TAE operations. Results All the cases with liver neoplasms were of affluent blood supply, The most lesion sizes demonstrated decrease at different degree. BeforeTAE operations, the mean area of 13 eases with enormous liver cancers was 13 cm× 12 cm, After TAE operations,it changed to 12 cm× 9 cm. Of the 6 cases with nodal cancers, the size was 6 cm×5 cm,4 cm×5 cm respectively. The abundant blood signals of the tumors changed significantly after TAE operation. The rich blood flow signals disappeared in 11 eases , decreased significantly in 16 cases and declined in 5 cases , The internal artery velocity of tumors before and after TAE operations was （56 ± 12） cm/s and （25 ± 12） cm/s respectively. There were markedly different （ P 〈 0.05 ）, The result of AFP tests also declined after TAE operation. Conclusions Color Doppler flow imaging is capable of assessing the interventional treatment of liver carcinoma.