51例静脉吸毒者病毒性肝炎感染的结果分析

Analysis of hepatitis virus in 51 cases of intravenous drug abusers

目的探讨静脉吸毒者五种常见病毒性肝炎感染的发生率及肝功能的改变。方法按常规抽血检测吸毒组和正常对照组人员五种病毒性肝炎标记物及肝功能指标。结果51例吸毒者感染各种病毒性肝炎共43人次,显著高于57例正常对照组(共8人次)(P<0.01),其中丙型、戊型肝炎感染情况尤为严重,感染率分别为45.1%和25.5%,显著高于正常对照组(3.5%,P<0.01);吸毒组肝功能指标AST、ALT均显著高于对照组(P<0.001)。结论静脉吸毒者易合并各种病毒性肝炎感染,其肝功能受损严重。

Objective To investigate the incidence of five kinds of virus hepatitis and the change of liver founetion among drug abuse via vein. Methods Various kinds of virus and liver function were determined as usual. Results 43 of 51 drug abuse patients were contracted by hepatitis virus. There is significant significance as compared to the control group （8/57, P 〈0.01 ） . The incidence of HCV （45.1%） and HEV （25.5%） are predominant among the drug abuse patients compared to the control group （3.5% , P 〈0. 01 ） . The levels of ALT and AST are significantly higher than that of the control group （P 〈 0. 001 ） . Conclusion Intravenous drug abusers are liable to infect by various hepatitis viruses and their liver functons are seriously affected.