婴幼儿肺炎血清心肌酶谱和肌钙蛋白Ⅰ的测定

Detection of the serum myocardial zymogram and cardiac troponin Ⅰ in infant with pneumonia

目的探讨婴幼儿肺炎血清心肌酶谱和肌钙蛋白Ⅰ(cTnⅠ)的变化。方法选择88例婴幼儿肺炎患儿,其中普通组56例,重症组32例,于入院后24h和住院治疗第7天抽血检测心肌酶谱和肌钙蛋白Ⅰ。结果婴幼儿肺炎患儿血清心肌酶谱存在异常增高,尤以重症肺炎为著,P<0.01。急性期与治疗1周后心肌酶谱差别有统计学意义,P<0.01。肺炎心衰组cTnⅠ值与普通肺炎组、对照组增高,P<0.01。结论婴幼儿肺炎时存在血清心肌酶谱和cTnⅠ异常,病情愈重,心肌损害愈明显。

Objective To inestigate the changes of serum myocardial zymogram and cardiac troponin Ⅰ（cTn Ⅰ ） in infant with pneumonia. Methods Eighty - eight infant pneumonia cases were devided into two groups：the common pneumonia group and serious heart failure group, and 40 normal infants as control group were chosen. Tested their serum myocardial zymogram and cTn Ⅰ after hospitalization, and after 1 week＇s treatment. Results Myocardial zymogram were increased in infantile pneumonia, especially in severe cases, P 〈 0. 01. After treatment in serious heart failure group,the level of myocardial zymogram and cTn Ⅰ partly recovered, P 〈0. 01. The cTn Ⅰ was increased in heart failure group, P 〈 0.01, Conclusion Pneumonia can cause the changes of the serum myocardial zymogram and cTn Ⅰ. With the progress of the patient＇s condition, the myocardial injury is increasing obvious,