睡眠呼吸暂停综合征患者生存质量状况及其影响因素

Quality of life in patients with sleep apnea syndrome and its influencing factors

目的:评价睡眠呼吸暂停综合征患者的生存质量状况,并对相关影响因素进行分析。方法:采用世界卫生组织WHOQOL-BREF简表,对2003—2005年两家省级医院150例患者进行生存质量问卷调查,运用单因素K-W检验和多元逐步回归等方法对相关因素进行分析。结果:睡眠呼吸暂停综合征生存质量评分较低,生理领域评分最低。社会因素(生活习惯、婚姻状况等)、医学因素(体块指数、呼吸暂停指数等)、自我评价(总体评分、自身健康评分等)和中医征候(气阴两虚、痰气互结等征)对生存质量影响有显著性意义。结论:中医征候、社会因素、医学因素、自我评价对生存质量状况有影响,针对证型对生存质量影响领域的不同,辩病与辨证论治相结合,能更好的改善生存质量状况。

Objective：To assess the quality of life（QOL） in patients with sleep apnea syndrome（SAS） and its＇ influencing factors. Method： One hundred and fifty cases of SAS patients of two province hospitals from 2003 to 2005 years were surveyed and their QOL were evaluated with WHOQOL-BREF, its＇ influencing factors were analyzed by Kruskal-Wallis test and step wise regression.Result：The scores of QOL of SAS patients were generally low,especially in physiological field. Social factors （life habit,marriage condition, etc）,medical factors （body mass index,apnea hypoventilation index, etc）,self assessment （total score,self healthy score, etc） and syndromes of TCM （deficiency of both Qi and Yin,interties phlegm and QI, etc） were significant in statistics of QOL.Conclusion： Social factors,medical factors,self assessment and syndromes of TCM affected the QOL of SAS significantly. The combination of applying treatment based on differentiation of syndrome and disease could improve the QOL of SAS better on the base of different syndrome.