青中年脑梗死患者的颈动脉超声、血脂、血糖、血粘度变化

Relationship between young and middle-aged patients with cerebral infarction with carotid ultrasound,lipidemia,blood glucose and viscosity

目的探讨青中年脑梗死患者的颈动脉超声、血脂、血糖、血粘度变化。方法对52例青中年脑梗死患者及38例非糖尿病、非冠心病、非脑梗死对照者作颈动脉超声检测,观察颈动脉粥样硬化斑块的数目、性质和颈动脉内径,并作血脂、血糖、血粘度测定。结果脑梗死组颈动脉粥样硬化斑块的发生率(53.85%),颈总动脉(CCA)内膜-中层厚度(IMT)和CCA内径与对照组比较差异有显著性(均P<0.01),以软斑为主(60.1%)。脑梗死组血糖、总胆固醇、三酰甘油及血粘度较对照组显著增高(均P<0.01)。结论青中年脑梗死患者大多有颈动脉粥样硬化、血脂、血糖、血粘度水平异常,对其进行早期干预,对预防脑梗死的发生有重要临床意义。

Objective To study the relationship among young or middle-aged patients with cerebral infarction with carotid ultrasound,blood lipid,blood glucose and viscosity.Methods 52 young or middle-aged patients with cerebral infarction and 38 patients without diabetes mellitus, CHD, cerebral infarction were studied as test group and control group. The number and property of carotid athereselerotie plaque and inner diameter of carotid artery were assessed by Doppler ultrasonography in all the patients,as well as blood lipid,blood glucose and vlseosity were evaluated. Results In test group,the rote of carotid atheroselerotie plaque was 53.85% ,the IMT and inner diameter of common carotid artery in test group were significantly different from control group （ all P 〈 0.01 ） ,and most of the athereselerotie plaques （60.1% ） were soft plaques. The levels of blood total cholesterol, triglyeeride and viscosity were obviously higher in test group, than those ineontrol group （ all P 〈 0.01 ）. Conclusion Atheroselerotie plaque and metabolic disorders included blood lipid, blood glucose and viscosity are the common phenomena in the patients of young or middle-aged patients with cerebral infarction. Early intervention of carotid atheresclerotic plaque and metabolic disorders in young or middle-aged patients is important for prevention of cerebral infarction.