针刺足三里、悬钟对缺血性中风患者脑血管功能的影响:多中心随机对照研究

Multicentral randomized controlled study on effects of acupuncture at Zusanli (ST 36) and Xuanzhong (GB 39) on cerebrovascular function in the patient of ischemic stroke

目的:探讨针刺足三里、悬钟对缺血性中风患者脑血管功能的影响。方法:采用3中心、单盲、随机、对照研究方法,将160例患者随机分为针刺组与对照组,每组各80例,两组均予以常规缺血性中风治疗,针刺组在此基础上结合针刺足三里、悬钟,以治疗前后TCD脑血管血流指数的变化情况进行两组疗效评价。结果:针刺组脑血管舒缩反应能力、脑血流自动调节功能、大脑半球侧支循环代偿功能较治疗前均显著加强(P<0·05,P<0·01),且均优于对照组(P<0·05)。结论:针刺足三里、悬钟对缺血性中风患者脑血管舒缩反应能力、脑血流自动调节功能、大脑半球侧支循环代偿功能有明显改善作用。

Objective To explore effect of acupuncture at Zusanli （ST 36） and Xuanzhong （GB 39） on cerebrovascular function in the patient of ischemic stroke. Methods Three central, single blind, randomized controlled trial method was adopted, and 160 cases were randomly divided into an acupuncture group and a control group, 80 cases in each group. The two groups were treated by routine treatment for ischemic stroke with acupuncture at Zusanli （ST 36） and Xuanzhong （GB 39） added in the acupuncture group. Changes of TCD cerebrovascular blood flow indexes before and after treatment were evaluated. Results After treatment, TCD indexes significantly improved in the acupuncture group （P〈0. 05, P〈0. 01） with a significant difference as compared with that in the control group （P〈0. 05）. Conclusion Acupuncture at Zusanli （ST 36） and Xuanzhong （GB 39） can significantly improve cerebral vasomotoricity, cerebral blood flow auto-regulative function, cerebral hemisphere collateral circulation comprehental function in the patient of ischemic stroke.