摘要
目的:探讨在急性心肌梗塞患者冠状动脉支架术后(PTCA)明胶酶的变化;方法:15例确诊为单支血管病变的急性心肌梗塞患者,在PTCA术前及术后5分钟内冠状动脉窦内取抗凝血2ml,利用Gelatin-PAGE法测冠状动脉内明胶酶的活性表达;结果:在术后明胶酶A比术前高(P<0.05),明胶酶B与术前无明显变化(P>0.05)。结论:明胶酶可能参与支架术后再狭窄过程。
AIM：To investigate the changes of gelatinase after stent implantation in sigle vessel disease patiens. METHODS： The activity of gelatinaseA and gelatinase B in coronary blood are detected by zymagraphy in 15 acute myocardial infartion who are sigle vessel disease patiens before and after stent implatation （befor PTCA and after PTCA） ;RESULT ：The indexes of the expression of gelatinaseA after PTCA were higher than those before PTCA , P 〈0. 05 ; the indexes of gelatinase B have no different between before PTCA and after PTCA （P〉0.05）. CONCLUSION： Gelatinase maybe participate the restonis after stent implantation.
出处
《中国分子心脏病学杂志》
CAS
2003年第1期18-20,共3页
Molecular Cardiology of China
关键词
PTCA
明胶酶
心肌梗塞
Gelatinase
PTCA
acute myocardial infartion
