摘要
从传统中药羌活中分离得到1个香豆素类化合物,应用1D和脉冲梯度场反相2DNMR检测技术(gCOSY,gNOESY,gHMQC,gHMBC)研究了其结构,鉴定为6-′O-(反式阿魏酰基)-紫花前胡苷,命名为羌活苷(Forbesoside).本文对其碳氢NMR信号进行了全归属.对从伞形花内酯衍生化为7-去甲基软木花椒素、紫花前胡苷元和6-′O-(反式阿魏酰基)-紫花前胡苷的NMR信号变化规律以及糖残基NMR信号归属方法进行了讨论和总结.
A series of 1D (^1H and ^13C NMR, DEPT experiment) and 2D NMR (including gCOSY, gHSQC and gHMBC) techniques were applied to the assignment of all proton and carbon signals of forbesoside [6'-O -(trans feruloyl)-nodakenin] which was a new coumarins compound isolated from the underground parts of Notopterygium forbesii Boiss. and Notopterygium incisum Ting ex H. T. Chang and with anti-inflammatory bioactivity. The NMR signals changed rules from umbelliferone to 7-demethylsuberosin, nodakenetin, nodakenin and forbesoside, and of acyled hydroxymethyl moiety of glucopyranosyl group, and methods of NMR signals assignment of saccharide were discussed and summarized.
出处
《波谱学杂志》
CAS
CSCD
北大核心
2006年第4期429-442,共14页
Chinese Journal of Magnetic Resonance