一种新的免疫抑制剂FTY720的NMR研究

Structure Elucidation of A New Immunosuppressant FTY720 by NMR

应用核磁共振技术(1H NMR,13C NMR,DEPT,HSQC,HMBC)确定了一种新的免疫抑制剂FTY720(2-氨基-[2-(4-辛基苯基)乙基]-1,3-丙二醇盐酸盐)的结构,准确归属了它的1H,13C信号.

NMR （^1H NMR, ^13C NMR, DEPT, HSQC, HMBC） methods were used to elucidate the structure of a new immunosuppressant FTY720 （2-amino- [-2-（4-octylphe- nyl） ethyl]-1, 3 propanediol hydrochloride）. The ^1H and ^13C chemical shifts of the compound were assigned.