摘要
目的：观察硝苯啶对妊高征孕妇微循环的影响。方法：采用微循环显微仪观察３０例正常孕妇和７６例妊高征孕妇，舌下含化硝苯啶２０ｍｇ前后甲襞微循环的变化。结果：硝苯啶有增加微循环血流速度、减轻红细胞聚集和扩张微血管管径的作用。服药前后轻、中度妊高征孕妇甲襞微循环积分比较，差异有显著性（Ｐ＜０．０５）。重度妊高征孕妇甲襞微循环积分服药前后比较，差异无显著性（Ｐ＞０．０５）。
Objectives:Tostudytheefectsofnifedipineonthemicrocirculationinpregnancy-in-ducedhypertension(PIH).Methods:Weobservedthemicrocirculationinnailfoldof30normalpreg-nantwomenand76casesofPIH.20mgnifedipinewasgivenandnailfoldmicrocirculationwasob-servedafter30minites.Results:Nifedipineincreasedthevelocityofbloodflow,reducedtheaggre-gationoferythrocytes,anddilatedcapilaries.Aftertheadministrationofnifedipine,thetotalscoreofthenailfoldmicrocirculationdecreasedsignificantlyinmildandmoderatePIH(P<0.05),butnomarkeddiferencewasobservedinseverePIHcases(P>0.05).Conclusion:Thedisorderofthemi-crocirculationofPIHcanbeimprovedbynifedipine.
出处
《中华妇产科杂志》
CAS
CSCD
北大核心
1996年第11期673-675,共3页
Chinese Journal of Obstetrics and Gynecology
关键词
硝苯地平
妊娠并发症
高血压
微循环
NifedipinePregnancycomplication,cardiovascularHypertensionMicro-circulation
