期刊文献+

雌激素治疗绝经后女性压力性尿失禁的临床和尿动力学观察 被引量:3

下载PDF
导出
摘要 目的观察雌激素补充治疗对绝经后女性压力性尿失禁的治疗效果。方法采用前瞻性研究方法,比较33例绝经后女性压力性尿失禁患者服用雌激素前后临床症状及尿流动力学结果的变化。结果Ⅰ型患者临床症状缓解率达68%,Ⅱ型及Ⅲ型患者的缓解率则分别只有44%和15%。Ⅰ型患者服药前Valsalva漏尿点压力(VLPP)、咳嗽漏尿点压力(CLPP)、最大尿道闭合压(MUCP)、功能尿道长度(FUL)分别为(120.5±23.6)㎝H2O、(130.7±21.6)㎝H20、(106.8±24.3)㎝H2O和(3.5±0.8)㎝H2O,服药后分别为(130.8±20.3)㎝H2O、(140.3±20.4)㎝H2O、(119.7±26.9㎝H2O和(3.9±1.0)㎝H2O,其前后差异有统计学意义,而Ⅱ型和Ⅲ型患者治疗前后无明显差异。结论单用雌激素治疗对Ⅰ型绝经后尿失禁患者有治疗效果,而对于Ⅱ、Ⅲ型患者合用其他治疗方法以达到最佳治疗效果。
出处 《江西医药》 CAS 2006年第10期749-750,共2页 Jiangxi Medical Journal
  • 相关文献

参考文献4

二级参考文献50

  • 1Fleischmann N, Christ G, Sclafani T, et al. The effect of ovariectomy and long- term estrogen replacement on bladder structure and function in the rat. J Urol,2002,168(3) :1265 - 8.
  • 2Rodriguez LV, Wang B, Shortliffe LM. Structural changes in the bladder walls of pregnant and hormone - treated rats: correlation with bladder dynamics. BJU Int,2004,94(9): 1366 - 72.
  • 3Mitesh H, Parek H, Paul C, et al. Effect of castration on female rabbit bladder physiology and morphology. Urol,2004,64(5): 1048 - 51.
  • 4Ken A, Takashi S, Seiji M, et al. The effect of ovariectomy and estradiol on rabbit bladder smooth muscle contraction and morphology. J Urol,2003,170(2pt1) :634 - 7.
  • 5Paul H,Rat Z,Kurt A,et al. Differential effects of sex hormones and phytoestrogens on peak and steady state contractions in isolated rabbit detrusor. J Urol, 1999,162(5): 1821 - 8.
  • 6Ofer Z, Shenfel D, Kurt A, et al. Rapid effects of estrogen and progesterone on tone and spontaneous rhythmic contractions of the rabbit bladder. Urol res,1999,27(5) :386-92.
  • 7Nicole D, Christo E. Age dependent response to exogenous estrogen on micturition, contractility and cholinergic receptors of the rat bladder. Life Sciences, 1999,64(23) :278 - 89.
  • 8Deirdre R,Thomas CR, Laura RC. The effects of delayed hormone replacement therapy on estrogen receptors of the cynomolgus monkey bladder and vagina. Neurourol Urodynam, 1998,17(3):241- 7.
  • 9Tsai E, Yang C, Chen H, et al. Bladder neck circulation by Doppler ultrasonography in postmenopausal women with urinary stress incontinence. Obstet Gynecol,2001,98(1) :52 - 6.
  • 10Zhu Q, Ritchie J, Marouf N, et al. Role of ovarian hormones in the pathogenesis of impaired detrusor contractility:evidence in ovariectomized rodents. J Urol,2001,166(3): 1136 - 41.

共引文献73

同被引文献72

引证文献3

二级引证文献22

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部