2Al-Ani B,Hansen KK,Hollenberg MD.Proteinaseactivated receptor-2:key role of amino-terminal dipeptide residues of the tethered ligand for receptor activation.Mol Pharmacol,2004; 65(1):149
4Tabei I,Hashimoto H,Ishiwata I,et al.New approach for the establishment of an hepatocyte cell line derived from rat early embryonic stem cells.J Hum Cell,2003;16(1):39
5Cederqvist K,Haglund C,Heikkila P,et al.High expression of pulmonary proteinase-activated receptor 2 in acute and chronic lung injury in preterm infants.Pediatr Res,2005;57(6):831
6Bolton SJ,McNulty CA,Thomas R J,et al.Expression of and functional responses to proteaseactivated receptors on human eosinophils.J Leukoc Bio,2003;74(1):60
7Schmidlin F,Amadesi S,Dabbagh K,et al.Protease-activated receptor 2 mediates eosinophil infiltration and hyperreactivity in allergic inflammation of the airway.J Immunol,2002; 169(9):5315
8De-Campo BA,Henry PJ.Stimulation of proteaseactivated receptor-2 inhibits airway eosinophilia,hyperresponsiveness and bronchoconstriction in a murine model of allergic inflammation.Br J Pharmacol,2005;144(8):1100
9He SH,Akhmed A,Marianna() DA,et al.Inhibitors of Tryptase as Mast Cell-Stabilizing Agents in the Human Airways:Effects of Tryptase and Other Agonists of Proteinase-Activated Receptor 2 on Histamine Release.J Pharmacol Exp Ther,2004;309(1):119
1Asokananthan N, Graham PT, Fink J, et al. Activation of protease-activated receptor (PAR)-1, PAR-2, and PAR-4 stimulates IL-6, IL-8, and prostaglandin E2 release from human respiratory epithelial cells[J]. J Immunol, 2002; 168: 3577-3585.
2Schmidlin F, Amadesi S, Dabbagh K, et al. Protease-activated receptor 2 mediates eosinophil infiltration and hyperreactivity in allergic inflammation of the airway[J]. J Immunol, 2002; 169:5315-5321.
3O'Brien PJ, Molino M, Kahn M, et al. Protease activated receptors: Theme and variations[J]. Oncogene, 2001; 20:1570-1581.
4Cottrell GS, Amadesi S, Schmidlin F, et al. Protease-activated receptor 2: Activation, signalling and function[J]. Biochem Soc Trans, 2003; 31:1191-1197.
7Ossovskaya VS, Bunnett NW. Protease-activated receptors: contribution to physiology and disease [J]. Physiol Rev, 2004, 84(2): 579-621.
8Schmidlin F, Amadesi S, Vidil R, et al. Expression and function of proteinase-activated receptor 2 in human bronchial smooth muscle[J]. Am J Respir Cfit Care Med, 2001, 164(7): 1276-1281.
9Hjortoe GM, Petersen LC, Albrektsen T, et al. Tissue factor-factor Ⅶa-specific up-regulation of IL-8 expression in MDA-MB-231 cells is mediated by PAR-2 and results in increased cell migration[J]. Blood, 2004, 103(8): 3029-3037.
10Caruso R, Pallone F, Fina D, et al. Protease-activated receptor-2 activation in gastric cancer cells promotes epidermal growth factor receptor trans-activation and Proliferatian[J]. Am J Pathol, 2006, 169 (1): 268-278.