上腔静脉综合征40例临床分析

An Analysis of Forty Cases with Superior Vena Cava Syndrome

对我科1989年12月至1994年9月收治的40例合并上腔静脉综合征的癌瘤病人作一临床分析.其中肺癌病人29例占73%,恶性淋巴瘤7例占18%,纵隔转移癌4例占10%.治疗全部采用抗肿瘤药物的化学治疗(以下简称化疗)和内科对症处理,有效率88%,尤其对小细胞肺癌和恶性淋巴瘤有效率高达100%.资料显示用化疗加内科对症处理治疗由恶性肿瘤引起的上腔静脉综合征(SVCS)疗效高、见效快,无明显的毒副作用,不失为一种首选的治疗手段.

Most patients with superior vena cava syndrome (SVCS) were caused by malignancies. The common causes were small cell lung cancer .malignant lymphoma and mediastinaltumors. Its clinical manifestations were often acute or subacute crises and emergent therapy was always needed to release symptoms. 40 cases of various tumors complicated with SVCS admitted in our department from December 1989 to September 1994. There were 29 cases with lung cancer (73%),7 with malignant lymphoma (17%) and 4 with mediastinal tumor (10%). All patients were treated with chemotherapy and palliative measures,such as oxygen administration, dehydration, diuretics and steroids. The total response rate was 88%. The highest response rate (100%) was achieved in lung cancer (especially the small cell lung cancer) and malignant lymphoma. The results showed that with above measures to treat SVCS caused by malignancies the effect was reliable and no obvious toxic and side effects was found. It suggests that these approaches might become the first choice of therapy for SVCS.