思密达加铁苋综合保健疗法治疗腹泻型肠易激综合征的临床研究

Clinical study of combination of Smecta,Tiexian and health protection treatment on diarrheic irritable bowel syndrome

目的观察思密达加铁苋综合保健疗法治疗腹泻型肠易激综合征的疗效及安全性。方法将患者随机分为2组,治疗组36例给予思密达口服及铁苋水煎服,同时辅以提、松肛腹式呼吸、保健按摩治疗;对照组33例给予思密达、易蒙停为主口服治疗。观察2组患者主要症状变化及药物不良反应。结果2组总有效率无显著性差异(P>0.05);药物不良反应1、a的痊愈率及总好转率有高度显著性差异(P<0.005);大便频率恢复正常时间及性状好转时间和排便伴随症状好转时间都有显著性差异(P<0.05)。结论思密达加铁苋综合保健疗法治疗腹泻型肠易激综合征疗效肯定,不良反应少,有临床应用价值。

Objective It is to observe the clinical efficacy and safety of Smeeta combined with Tiexian and health protection treatment on diarrheic irritable bowel syndrome （DIBS）. Methods The patients were randomly divided into 2 groups. 36 cases of patients in treatment group were treated with Smecta and Tiexian by oral administion, plus raising and relaxing anus abdominal respiration and therapeutic massage. 33 cases of patients in control group were treated with Smecta and Loperamide by oral administion. The changes of the patients＇ main symptoms and adverse reaction before and after treatment were observed. Results Compared with each other, the was no significant difference in total effective rate （P 〉 0.05）, and very significant differences in adverse reaction and recovery rate and total improvement rate after one year（P 〈 0. 005）. There were also differences in normal time of defecation frequency and improvement of stool quality and the following symp- toms of defecation（P 〈 0.05）. Conclusion The therapeutic effect of Smecta combined with Tiexian and health protection treatment on DIBS is definite and with less adverse reaction, so it is worth using in in clinic.