正常前列腺外周带3DMRS定量分析

Quantitative analysis of normal prostate peripheral zone with 3DMRS.

目的定量分析正常成年男性前列腺外周带的三维磁共振波谱(Three-dimensional magnetic resonance spec-troscopy 3DMRS)。方法收集20例无前列腺临床症状的患者行前列腺3DMRS检查,收集正常前列腺外周带的3DMRS资料,对胆碱复合物[胆碱(Choline)+肌酸(Creatine)]/枸橼酸盐(Citrate)的比值(CC/C)进行统计学分析,对年龄组间和6分区间CC/C数值进行独立样本t检验。结果20例正常前列腺外周带的CC/C比值均值为0.38±0.2(99%可信区间),年龄组间和6分区间该比值差异无显著性(P>0.05)。结论正常前列腺代谢情况可用3DMRS来定量评价。正常前列腺外周带胆碱复合物浓度及波峰较低,枸橼酸盐的浓度及波峰较高,正常成年男性前列腺外周带不同区间代谢产物无显著差异,也无年龄差异。

Objective To evaluate the metabolic level of normal prostate peripheral zone quantitatively with 3DMRS. Methods 20 cases without eUnieal indication of prostate disease were examined using 3DMRS and the prostate peripheral zone metabolic ratio of （ Choline ＋ Creating）/eitrate （CC/C） was determined . Results The mean ratios of CC/C in the peripheral zone of different individuals were not significantly different（ P 〉 0.05） and the mean value was 0.38 ± 0.2（ IC = 99% ）. There no significant differenees were observed among different age groups （ P 〉 0.05）. Conclusion The metabolic level of normal prostate can be evaluated with 3DMRS quantitatively.