我院口服降糖药及合并用药分析

Analysis of Use of Oral Hypoglycemic Drugs either Alone or In Combination with Other Drugs in Our Hospital

目的:分析我院口服降糖药的使用情况,为临床合理用药提供参考。方法:随机抽取2005年3月份含有口服降糖药处方,并进行统计分析。结果:1 069张处方中,患者平均年龄(63.88±12.00)岁,有54.07%(578/1 069)伴有并发症和/或合并症。降糖药单一用药64.27%(687/1 069),联合用药占35.73%(382/1 069)。单一用药中居前3位的分别是α-糖苷酶抑制剂、磺脲类、双胍类;联合用药中居前3位的分别是:磺脲类+α-糖苷酶抑制剂、磺脲类+双胍类、双胍类+α-糖苷酶抑制剂。结论:本次调查的口服降糖药用药基本合理,仅少数几例存在问题,如磺脲类药物联合应用及胃肠道溃疡患者的用药。

OBJECTIVE：To analyze the application of oral hypoglycemic drugs, so as to provide some references for rational use of which in the clinic. METHODS： The outpatient oral hypoglycemic drug prescriptions in March, 2005 were randomly collected for statistical analysis. RESULTS： Of 1 069 prescriptions, patients＇ mean age was 63.88 ± 12.00 years, 54.07% （578/1 069） had complications, 64.27% （687/1 069） were treated with oral hypoglycemic drugs alone, and 35.73 % （382/1 069） were treated with oral hypoglycemie drugs in combination with other drugs. Leading the first 3 places on the list of single drug use were leading the first 3 places on the list α - Glycosidace inhibitor, sulfonylureas of drug combination were sulfonylureas in （SURs） and biguanide, respectively; while combination with α- Glyeosidace Inhibitor. CONCLUSION： The utilization of oral hypoglycemic drugs in our hospital was found to be basically rational; however, the use of drugs in a few cases is far from perfect, such as the drug combination of sulfonylureas, the choices of drugs for patients with gastrointestinal ulcer.