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70例肝硬化患者IL-6和TNF-α的临床研究 被引量:1

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摘要 目的:探讨肿瘤坏死因子(TNFα-)和白细胞介素-6(IL-6)于肝硬化发病和转归相关性。方法:用双抗体夹心法和IL-6反应细胞株CESS测定法分别检测肝硬化70例患者血浆中TNFα-和IL-6水平。结果:患者血清中的IL-6和TNFα-和反映肝纤维化指标质酸(HA)、Ⅳ胶原-C(Ⅳ-C)、层粘蛋白(LN)均高于正常组(P<0.001)。TNFα-和IL-6与HA、LN、Ⅳ-C水平均呈显著正相关。结论:TNFα-和IL-6水平于肝硬化程度密切相关,并可反映肝脏损害的程度。
出处 《长春中医药大学学报》 2006年第4期50-50,共1页 Journal of Changchun University of Chinese Medicine
关键词 肝硬化 IL-6 TNF-Α
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