广西华支睾吸虫病流行及危险因素分析

The prevailing status and risk factors analysis of the Clonorchiasis in Guangxi Autonomous Region

目的了解广西华支睾吸虫病流行现状、流行态势和影响因素,为制定有针对性的防治措施提供科学依据。方法按流行程度和水系流域进行分层整群随机抽样;采用改良加藤厚涂片法检查,并进行虫卵计数;对居民进行问卷调查并收集资料,分析相关危险因素。结果全区调查9个县(市)27个点共13990人。华支睾吸虫平均感染率为9.76%,平均EPG为1083。男性平均感染率为女性的2.22倍(13.09%/5.89%),前者平均EPG为后者的2.01倍(1320/658)。各年龄组均有感染,以成人感染为重。汉族感染率为11.56%,居首位,高于壮族(8.17%),但壮族平均EPG为1470,高于汉族(902)。职业分布以医师、教师,农民和行政干部感染为主。结论广西华支睾吸虫病地区分布差异大,局部地区流行严重;青壮年是主要危害群体;吃生鱼及用新鲜粪便喂鱼是最重要的危险因子。

Objective To analyze of Clonorchis sinensis （C. sinensis） in the current status, risk factors and transmission trend of human infection Guangxi Zhuang Autonomous Region in order to provide updated information for the development of control measures. Methods A province wide survey on C. sinensis had been done. It was camed on the method of sampled by stratified random sampling based on the prevalent degree and the river valley. The fecal examination was conducted by Kato - Katz method, and the total amount of eggs was calculated.Survey of the local people and collection of the relevant data were conducted to analyze the relevant transmission factors of C.sinensis. Results A total of 13990 people from 27 villages in 9 counties （cities） were checked. The average prevalence of C. sinensis infection in the residents was 9.76% and the mean EPG（eggs per gram of faeces） was 1083.The prevalence in the male was 13.09% ,2.22 times of that in the female （5.89%） ; the mean EPG in the male was 1320,2.01 times of that in the female （658） .The infection was found in every age group and remained at a higher level in adults. Among ethnical groups, On the top of the prevalence rate list is the Han nationality （11.56% ）, higher than Zhuang nationality（8.17%）, but the mean EPG in Zhuang nationality was 1470, more than Han nationality （902） .The C. sinensis egg positive rates in doctors, teachers, peasants and carders remained the highest among the investigated people. Conclusions Significant difference in prevalence was found in different counties, and the prevalence is serious in certain areas in Guangxi. The adults are the main infected community. The survey revealed that eating raw fish or feeding fish with raw fecal is the main risk factor responsible for the transmission of the parasite.