期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

放射性脑损伤发病机制及免疫系统改变的研究 被引量：2

Study of pathogenesis and the change of immune system of radiation brain injury
原文传递
导出
摘要 放射性脑损伤是头颈部肿瘤放射治疗后的一种严重并发症,本文从放射性脑损伤发病机制及电离辐射引起免疫系统改变的基础上推断放射性脑损伤可能引起的免疫系统改变。 Radiation brain injury is a severe comphcation of the pate tumour after radiotherapy. Review the pathogenesis of radiation brain injury and ion irradiation and the change of immune system then conclude the change of immune system that radiation brain injury can cause.
作者 钟静 姜恩海
机构地区 中国医学科学院中国协和医科大学放射医学研究所临床室
出处 《国际放射医学核医学杂志》 2006年第5期301-304,共4页 International Journal of Radiation Medicine and Nuclear Medicine
关键词 脑损伤 辐射损伤 免疫系统 Brain injury Radiation injury Immune system
分类号 R818.74 [医药卫生—放射医学]
  • 相关文献

参考文献15

  • 1唐亚梅,邢诒刚,吕瑞妍,杨炼红,王艺东.大鼠脑照射后学习记忆力下降及脑损伤修复的研究[J].中华放射医学与防护杂志,2004,24(2):130-131. 被引量：4
  • 2Romero AA,Gross SR,Cheng KY,et al.An age-related increase in resistance to DNA damaged-induced apoptotic cell death is associated with development of DNA repair mechanisms.J Neurochem,2003,84(6):1275-1287.
  • 3Gobbel GT,Chan PH.Neuronal death is an active,caspasedependent process after moderate but not severe DNA damage.J Neurochem,2001,76(2):712-720.
  • 4张燕,陈肖华.中枢神经系统辐射损伤的细胞与分子机制研究进展[J].国外医学（放射医学核医学分册）,2004,28(1):41-44. 被引量：2
  • 5Tofilon PJ,Fike JR.The radioresponse of the central nerous system:a dynamic process.Radiat Res,2000,153(3):357-370.
  • 6高荣莲,陈肖华.星形胶质细胞的电离辐射损伤及修复作用[J].国外医学（放射医学核医学分册）,2004,28(1):37-40. 被引量：7
  • 7Kutita H,Kawahara N,Asai A,et al.Radiation-induced apoptosis of oligodendrocytes in the adult rat brain.Neurol Res,2001,23(8):869-874.
  • 8Cammer W.Effects of TNF alpha on immatuare and mature oligodendrocytes and their progenitors in vitro.Brain Res,2000,864(2):213-219.
  • 9Pena LA,Fuks Z,Kolesnick RN.Radiation-induced apoptosis of endothelial cells in the murine central nervous system:protection by fibroblast growth factor and sphingomyelinsae deficiency.Cancer Res,2000,60(2):321-327.
  • 10Kimura T,Sako K,Tohyama Y,et al.Diagnosis and treatment of progressive space-occupying radiation necrosis following steretactic radiosurguery for brain metastasis:value of proton magnetic resonance spectroscopy.Acta Neurochir (Wien),2003,145 (7):557-564.

二级参考文献50

  • 1Yuan H, Galoer MW, McColgan T, et al. Radiation-induced permeability and leukocyte adhesion in the rat blood brain barrier:modulation with anti-ICAM-1 antibodies[J]. Brain Res, 2003, 969(1-2): 59-69.
  • 2Akiyama K, Tanaka R, Sato M, et al. Cognitive dysfunction and histological findings in adult rats one year after whole brain irradiation[J]. Neurol Med Chir, 2001, 41(12): 590-598.
  • 3Ding GR, Nakahara T, Miyakoshi J. Exposure to power frequency magnetic fields and X-rays induces GAP-43 gene expression in human glima MO54 cells[J]. Bioelectromagnetics, 2002, 23(8): 586-591.
  • 4Janeczko K, Setkowicz Z, Fraczek M, et al. Effects of prenatal gamma-irradiation on postnatal astrogliogenesis in the hippocampal formation of rat[J]. Brain Res, 1999, 816(2):628-632.
  • 5Romero AA, Gross SR, Cheng KY, et al. An age-related increase in resistance to DNA damage-induced apoptotic cell death is associated with development of DNA repair mechanisms[J]. J Neurochem, 2003, 84(6): 1275-1287.
  • 6Pena LA, FuksZ, Kolesnick RN. Radiation-induced apoptosis of endothelial cells in the murine central nervous system: protection by fibroblast growth factor and sphingomyelinase deficiency[J]. Cancer Res, 2000, 60(2): 321-327.
  • 7Offer H, Erez N, Zurer I, et al. The onset of p53-dependent DNA repair or apoptosis is determined by the level of accumulated damaged DNA[J]. Carcinogenesis, 2002, 23(6):1025-1032.
  • 8Chong MJ, Murray MR, Gosink EC, et al. Atm and Bax cooperate in ionizing radiation-induced apoptosis in the central nervous system[J]. Proc Natl Acad Sci USA, 2000, 97(2): 889-894.
  • 9Raju U, Gumin GJ, Tofilon PJ. Radiation-induced transcription factor activation in the rat cerebral cortex[J]. Int J Radiat Biol, 2000, 76(8): 1045-1053.
  • 10Gobbel GT, Chan PH. Neuronal death is an active, caspasedependent process after moderate but not severe DNA damage[J]. J Neurochem, 2001, 76(2): 520-531.

共引文献22

同被引文献31

  • 1沈海林,沈纪芳,秦颂兵,芮春朵,唐健,许昌韶,周菊英,刘国强.大鼠全脑照射后早期放射性脑损伤的磁共振波谱与病理对照研究[J].临床放射学杂志,2005,24(9):818-823. 被引量：23
  • 2宋琼,夏黎明,王承缘,冯定义.超急性期放射性脑损伤的MRS和DTI研究[J].放射学实践,2007,22(7):687-690. 被引量：11
  • 3官键,陈龙华,李志勇,李启生,刘英,王宏梅.放射性脑损伤实验兔模型的建立[J].肿瘤防治研究,2007,34(7):477-479. 被引量：6
  • 4Rabinov JD, Brisman JL, Cole A J, et al. MRI changes in the rat hippocampus following proton radiosurgery. Stereotact Funct Neurosurg. 2004;82(4):156-164.
  • 5Chan KC, Khong PL, Cheung MM, et al. MRI of late microstructural and metabolic alterations in radiation-induced brain injuries. J Magn Reson Imaging. 2009;29(5): 1013-1020.
  • 6Caceres LG, Aon Bertolino L, Saraceno GE, et al. Hippocampal-related memory deficits and histological damage induced by neonatal ionizing radiation exposure. Role of oxidative status. 2010;1312:67-78.
  • 7石磊,郎晓燕,孙晶晶,等,鼻咽癌放疗后放射性脑病早期阶段MRI及SWI表现[A].2013年浙江省放射学学术年会论文集[C].2013年.
  • 8Buatti JM, Friedman WA, Theele DP, et al. The lazaroid U74389G protects normal brain from stereotactic radiosurgery-induced radiation injury. Int JRadiat Oncol Biol Phys. 1996;34(3):591.
  • 9Miot E, Hoffschir D, Alapetite C, et al. Experimental MR Study of Cerebral Radiation injury: Quantitative T2 Changes Over Time and Histopathologic Correlation. AJNR. 1995;16:79-85.
  • 10袁文佳,涂彧,崔凤梅.放射性脑损伤的发病机制及治疗[J].国际放射医学核医学杂志,2008,32(4):250-254. 被引量：2

引证文献2

二级引证文献14

国际放射医学核医学杂志
2006年 第5期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部