太原市SARS临床确诊病例血清抗体和影像学资料随访分析

Follow-up study on SARS-CoV antibody,lung and femoral head radiographic changes among SARS patients in Taiyuan,Shanxi province

目的了解山西省太原市SARS临床确诊病例半年后的血清抗体水平、胸部和股骨头影像学的变化。方法对132例太原市2003年3月11日～7月5日临床确诊的SARS病例进行随访问卷调查、血清学抗体检测及肺部和股骨头影像学检查，并分析比较。结果SARS临床确诊病例半年后的主要症状为气短、关节肌肉痛、心悸和烦躁；女性患者各种症状的发生率均高于男性；血清抗体与心悸、烦躁和肌肉关节痛的发生情况有统计学关联；血清抗体阳性率与入院时间有关联。结论太原市SARS病例存在过度诊断现象，血清抗体阳性率随着入院时间的推移逐步下降；部分确诊病例出院后合并股骨头缺血性坏死改变。

Objective To study the changes in serum SARS coronavirus （SARS-CoV） antibody and radiographic changes of lung and femoral head of SARS patients after six months discharged. Methods 132 SARS patients admitted to hospital from llth, March to 5th, July in 2003 were followed up for interview, SARS-CoV antibody testing and X-ray examination of chest and femoral head following a comparative analysis. Results The cardinal symptoms of SAIRS patients six months after discharged were tachypnea, arthralgia and myalgia, palpitation and fidget. The symptom occurrence rate of female was higher than that of male. Difference rate of SARS-CoV antibody was found among patients with arthralgia, palpitation or fidget. There was statistically significant difference between rate of SARS-CoV and time admission to the hospital. Conclusions Over SARS diagnosis might exist during SARS epidemic period in Taiyuan. Positive rate of SARS patients de-escalated with the process of admission to the hospital. In some patients femoral head necrosis occurred.