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Expression of semaphorin 6D in gastric carcinoma and its significance 被引量：1

Expression of semaphorin 6D in gastric carcinoma and its significance
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摘要 AIM: To investigate the protein and mRNA expression of semaphorin 6D in gastric carcinoma and its significance. METHODS: The protein and mRNA expression of semaphorin 6D was detected by semi-quantitative rever- se transcription PCR and Western blotting respectively in 30 cases of gastric carcinoma and normal gastric mucosa. RESULTS: The protein and mRNA expression of semaphorin 6D in gastric carcinoma was significantly higher than that in normal gastric mucosa (0.24 ± 0.06 vs 0.19 ± 0.07, 0.26 ± 0.09 vs 0.20 ± 0.10, P < 0.05). CONCLUSION: Semaphorin 6D may play an important role in the occurrence and development of gastric carcinoma, and is related to tumor angiogenesis. AIM： To investigate the protein and mRNA expression of semaphorin 6D in gastric carcinoma and its significance. METHODS： The protein and mRNA expression of semaphorin 6D was detected by semi-quantitative reverse transcription PCR and Western blotting respectively in 30 cases of gastric carcinoma and normal gastric mucosa. RESULTS： The protein and mRNA expression of semaphorin 6D in gastric carcinoma was significantly higher than that in normal gastric mucosa （0.24 ± 0.06 vs 0.19 ± 0.07, 0.26 ± 0.09 vs 0.20 ± 0.10, P 〈 0.05）. CONCLUSION： Semaphorin 6D may play an important role in the occurrence and development of gastric carcinoma, and is related to tumor angiogenesis.
作者 Xiang-Yang Zhao Lin Chen Qian Xu Yu-Hong Li
机构地区 Department of General Surgery Institute of Basic Medicine Department of Pathology
出处 《World Journal of Gastroenterology》 SCIE CAS CSCD 2006年第45期7388-7390,共3页 世界胃肠病学杂志（英文版）
关键词 血管生成 胃癌 胃粘膜 蛋白质 Semaphorin 6D Gastric carcinoma Norma gastric mucosa Angiogenesis
分类号 R735.2 [医药卫生—肿瘤]
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参考文献16

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World Journal of Gastroenterology
2006年 第45期

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