血管加压素联合肾上腺素抢救心脏骤停的临床观察

Administration of Vasopressin Combined with Epinephrine During Cardiopulmonary Resuscitation

目的:研究血管加压素联合肾上腺素对心脏骤停的疗效。方法:64例呼吸心跳骤停患者随机分为肾上腺素组(对照组)和血管加压素联合肾上腺素组(治疗组)各32例,观察自主心律恢复时间、1h有效率、24h有效复苏成功率。结果:对照组、治疗组自主心律恢复时间分别为(20.5±4.5)min、(8.5±3.5)min、1h有效率分别为38%、72%;24h有效复苏成功率分别为13%、44%。治疗组的自主心律恢复时间明显短于对照组,1h有效率、24h有效复苏成功率明显高于对照组。结论:对心脏骤停患者,在标准心肺复苏(CPR)中,联合应用血管加压素和肾上腺素,可有效缩短自主心律恢复时间,提高1h有效率和24h有效复苏成功率。

Objective： To research the effect of administration of vasopressin combined with epinephrine on cardiopulmonary resuscitation （CPR）. Methods： Sixty-four patients with cardiac arrest were divided into the control group and the observation group randomly. 32 cases in the control group were solely given epinephrine, the other 32 cases in the treatment group were given the combination of vasopressin and epinephrine. The survival rate in an hour, the suecess ratio of CPR in 24 hours and the time of spontaneous rhythm of the heart restoration was monitored in each group. Results： The average times of spontaneous rhythm of the heart restoration were （20.5±4.5） minutes and （8.5±3.5） minutes in the control group and treatment group respectively. The survival rates in an hour were 38% and 72%.The success ratios of CPR in 24 hours were 13% and 44%.The average time of spontaneous rhythm of the heart restoration in the treatment group was significantly shorter than that in the control group .The survival rate in an hour and the success ratio of CPR in 24 hours in the treatment group was obviously higher than that in the control group. Conclusions： During cardiopulmonary resuscitation , the vasopressin combined with the epinephrine, the average time of spontaneous rhythm of the heart restoration will be shorten, and the survival rate in an hour and the success ratio of CPR in the observation will be obviously improved.