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2型糖尿病患者血清脂联素水平与颈动脉粥样硬化的关系 被引量：4

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摘要 目的探讨2型糖尿病患者血清脂联素(APN)水平与颈动脉粥样硬化的关系。方法将54例2型糖尿病患者根据颈动脉内膜中层厚度(IMT)分成轻度组(IMT<1.0 mm,33例)和重度组(IMT≥1.0 mm或存在硬化斑块,21例),采用酶联免疫法测定血清APN,并与健康体检者进行比较。结果2型糖尿病患者血清APN水平显著低于对照组,重度组APN水平明显降低。血清APN与IMT呈显著负相关。结论脂联素可能具有抗动脉粥样硬化的作用,是糖尿病动脉粥样硬化的保护性因子。
作者 黄蔡华 侯亚莉
机构地区 湖北省武汉市普爱医院干部病房 湖北省武汉市普爱医院内分泌科
出处 《临床内科杂志》 CAS 2006年第12期845-846,共2页 Journal of Clinical Internal Medicine
关键词 2型糖尿病 脂联素 颈动脉内膜中层厚度
分类号 R587.1 [医药卫生—内分泌]
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临床内科杂志
2006年 第12期

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