吡啶二甲酸的合成及其应用

Synthesis of Pyridine-dicarboxylic Acid and Its Application

在含硫酸铜的酸性水溶液中,用氯酸钠作氧化剂,氧化喹啉得到2,3-吡啶二甲酸,产率为56·4%;以硫酸铜为催化剂,用浓硝酸在高温氧化异喹啉得到3,4-吡啶二甲酸,产率为71·4%,并讨论了影响合成的因素。在钼酸铵存在下,采用固相烘焙法,2,3-吡啶二甲酸和3,4-吡啶二甲酸分别与尿素和氯化亚铜作用得到了氮杂铜酞菁。实验发现,以3,4-吡啶二甲酸合成的氮杂铜酞菁在吡啶中具有较大的溶解度,最大吸收波长为673nm。

In the acidic aqueous solution of copper sulfate, pyridine-2,3-dicarboxylic acid was synthesized by oxidizing quinoline with sodium chlorate, and the yield of the product could reach 56.4%. Using copper sulfate as catalyst, pyridine-3,4-dicarboxylic acid was synthesized by oxidizing isoquinoline with concentrated nitric acid at high temperature, and the yield was 71.4%. The factors influencing on the synthetic reaction were discussed. Aza-copper phthalocyanine could be obtained by baking of pyridine-2,3-dicarboxylic acid or pyridine-3,4-dicarboxylic acid separately with urea and cuprous chloride in the presence of ammonium molybdate. It was found that aza-copper phthalocyanincs from pyridine-3,4-dicarboxylic acid had better solubility in pyridine, and the maximum absorption wavelength was 673nm.