糖尿病视网膜病变与全身多因素关系

THE RELATIONSHIP BETWEEN THE DIABETIC RETINOPATHY AND THE SYSTEMIC MULTI-FACTORS

目的:探讨糖尿病视网膜病变(DR)与全身多因素关系。方法:收集54例108眼2型糖尿病患者多项临床指标,依据其视网膜病变程度将其分为正常(NDR),非增殖性视网膜病变(NPDR)及增殖性视网膜病变(PDR)3组。分析3组DR程度与病程、血糖、血压和血脂的关系。结果:3组病程呈递增关系,NDR与NPDR及PDR差别有统计学意义;3组空腹血糖,餐后血糖及HbA1c呈递增关系,NDR与NPDR及PDR此三项指标差别有统计学意;NDR与PDR,NPDR与PDR组之间收缩压及舒张压差别均有统计学意;NDR与NPDR组甘油三酯,胆固醇和LDL差别及NPDR组与PDR组甘油三酯,LDL差别均有统计学意义。结论:病程预示DR的发生率及严重程度,血糖控制的好坏直接影响DR的发生发展,高血压,高血脂增加了DR发生及恶化的危险性。综合治疗具有重要意义。

Objective： To study the relationship between DR and the systemic multi- factors.Mothods： The clinical data of the 54 patients of type 2 diabetes were collected. The patients were divided into NDR group, NPDR group and PDR group according to the seriousness of DR. The association of DR with these clinical data was analyzed. Result： The duration become longer and the level of glycemia increased with NDR, NPDR and PDR, the difference of the two factors between the 3 groups was remarkable; There was significant difference between the 3 group in blood pressure and serum lipid too. Conclusion： The duration indicats the incidence; The controlling of glycemic affects the progression; Hypertension and hyperlipid increases the risk of incidence and deterioration. Combining treatment to DR is very important.