摘要
本研究采用小鼠精子畸形实验,就亚硒酸钠对醋酸铅诱发小鼠精子畸形率增高作用的影响进行了研究。结果表明,三种不同浓度的醋酸铅均可使小鼠精子畸形率明显增高,且呈剂量-反应关系,精子形态的改变主要是头部的无钩形、香蕉形及无定形。亚硒酸钠可以明显拮抗三种不同浓度的醋酸铅诱发的小鼠精子畸形率增高的作用。
The effect of sodium biselenite on suppression of the sperm abnormality by lead acetate in mice was studied.The results Showed that there was a dose-related increase in the frequency of sperms with abnormal head morphologies from mice treated with 12.5,25 or 50 mg lead acetate/kg body weight and this was antagonised by the injection of sodium biselenite (1.0mg/kg body weight).
出处
《延边医学院学报》
CAS
1996年第4期208-210,共3页
Journal of Medical Science Yanbian University
关键词
铅
醋酸盐类
硒
精子发生
lead acetate
biselenite
spermatogenesis