摘要
目的对系列抗晕船口服液进行安全性评价。方法进行小鼠最大耐受量试验。结果防晕船口服液基本无毒性,抗晕船口服液小鼠最大耐受剂量为临床剂量的100倍以上。结论按临床推荐剂量长期服用,安全有效,在体内不会产生蓄积作用。
Objective To conduct safety evaluation of serial antiseasickness oral sohltions for animal toxicology. Methods Maximum tolerance test of antiseasickness oral solution was pertbrmed in Kunming mice. Results Prevent- sick syrup was hontoxic. The mice maximum tolerance of anti-seasickness oral solution was 100 tinges higher than that of clinical dosage. Conclusion Anti-seasickness oral solution is safc for oral use ,taking clinieal dose for a long time might not result in accumulation in vivo.
出处
《中国药业》
CAS
2006年第20期17-18,共2页
China Pharmaceuticals
关键词
抗晕船口服液
防晕船口服液
毒理试验
最大耐受量
prevent- seasickness oral solution
anti- seasickness oral solutinn
toxicological test
maximum tolerance
