摘要
目的对膝痛宁膏贴的抗炎镇痛作用的有效性作科学评价。方法动物随机分组,设空白对照,选择功效与主治基本相似的麝香舒活精等为中药阳性药物对照,设膝痛宁膏贴的25%原药液、50%原药液与原药液3个剂量组与麝香舒活精组,服法外用,实验动物采用SD系大鼠,NIH系小鼠。结果膝痛宁与抗炎镇痛的全部指标影响与空白组有显著差异,麝香舒活精组对二甲苯致小鼠腹部皮肤毛细血管通透性增高及对醋酸致小鼠疼痛的指标与空白组无显著差异。
Objective：Scientific evaluation of the effect on antiphlogosis and abirritation of Xitongning Ointment. Methods： Random grouping for animals and setting blank comparison. Choose Shexiang Shuhuojing of similar efficacy and functions as the Yang medicament of Chinese traditional medicine for comparison. Set three dosage groups of Xitongning Ointment of 25 % of original liquid, 50 % of original liquid and original liquid and one group of Shexiang Shuhuojing. Directions：For external use. Use SD series big rat and NIH series small rat as experimental animals. Result：All index impact of Xitongning about antiphlogosis and abirritation evidently differ from the blank group. No evident differences between the blank group and Shexiang Shehuojing group on the increase of capillary permeability of mouse belly skin induced by xylene and the aching index of mouse induced by acetic acid.
出处
《中国中医骨伤科杂志》
CAS
2006年第6期57-60,共4页
Chinese Journal of Traditional Medical Traumatology & Orthopedics
基金
广州卫生局课题2003B017
