摘要
近年来,干细胞的研究进展,给心肌梗死的治疗带来了新的希望,干细胞移植也成为了当前研究的热点问题。骨髓干细胞、胚胎干细胞、骨骼肌成肌细胞等已被应用于心肌的再生。研究表明,干细胞移植能有效地改善梗死心肌的功能,但其作用机制尚不完全明了。本研究对干细胞移植治疗心肌梗死研究中取得的成就、有待解决的问题以及临床应用前景作了一个总的评述。
In recent years, transplantation of stem cells has become a hot field in research and treatment. The clinical application of stem cells is a promising strategy in the treatment of myocardium infarction. Bone marrow-derived stem cells, embryonic stem cells, skeletal myoblasts have been proposed for myocardial regeneration. The experimental studies have documented the efficacy of stem cells transplantation in improving function of infracted myocardial although the mechanisms involved in this improvement have not been elucidated. We present an overview of encouraging results and questions to be solved on this issue, and also provide an insight into the potential for clinical application of stem cells implantation in the treatment of myocardial infarction.
出处
《中国生物医学工程学报》
CAS
CSCD
北大核心
2006年第6期786-792,共7页
Chinese Journal of Biomedical Engineering
基金
天津市科技发展计划项目(05YFJZJC01601)
国家自然科学基金(30570471)
新世纪优秀人才支持计划(NCET-04-0222)
关键词
干细胞
移植
心肌梗死
stem cells
transplantation
myocardial infarction
