女性早期尿道癌膀胱黏膜尿道重建术的探讨(会议征文选登)

Study of the operation of reconstructing female urethra with bladder mucosa in female patients with early urethra cancer

目的:探讨应用膀胱黏膜重建女性尿道治疗女性尿道肉阜早期癌变的疗效。方法:对10例女性尿道肉阜早期癌变患者行一期膀胱黏膜尿道重建术,并作术前、术后6个月及术后1年最大尿流率测定。结果:10例均一期成形,术后随访1-9年,排尿正常,无肿瘤复发,无尿失禁及其他并发症,术前、术后6个月及术后1年最大尿流率测定差异有统计学意义(P(0.05)。结论:对于女性尿道肉阜早期癌变及早期原发性女性尿道癌患者,应用膀胱黏膜尿道一期重建术是可行的治疗方法,具有简单、安全、有效、并发症少等优点。

Objective：To investigate the efficacy of reconstructing urethra with bladder mucosa in female with urethra early cancerogenic caruncle. Methods： 10 cases of urethra early cancerogenic caruncle were given bladder mucosa flap procedure and one stage reconstructing urethra. Tests of Maximum flow rate were performed in all patients before operation and six months after operation and one year after operation respectively. Results： 10 cases treated with one stage reconstructing urethra by using bladder mucosa were followed up one year to 9 years after the operation respectively. The success rate of the operation was 100%. normally urinated, no incontinence and other complications, The statistical significance of Maximum flow rate can be seen among the time of before opera tion and six months after operation and one year after operation. Conclusions： It is feasible of reconstructing female urethra by using bladder mucosa one stage for treatment of early urethra cancerogenic caruncle and early primary urethral carcinoma . It is a simple, safe,effective and markedly lessened complication.