摘要
A novel Schiff base compound was synthesized by the reaction of paeonol and phenylpropanolamine in absolute methanol. It was characterized by elemental analyses, IR, tH NMR and X-ray single-crystal diffraction. The compound crystallizes in the wiclinic system, space group PI, with a = 6.4075（11）, b = 10.2821（18）, c = 12.573（2） A, α = 92.606（3）,β= 100.980（3）, γ = 90.994（3）°, V= 812.1（2） A3, Mr = 299.36, Z = 2, F（000） = 320, Dc=1.224 g/cm^3, T= 293（2） K,μ = 0.083 mm^-1 and 2 = 0.71073 A, the final R = 0.0555 and wR = 0.1619 for 2442 observed reflections with I 〉 2σ（I）. The colnpound was valued for its antimicrobial activity against bacterial strands using the agar diffusion method. It is found to be active against Candida albicans and Staphylococcus aureus.
A novel Schiff base compound was synthesized by the reaction of paeonol and phenylpropanolamine in absolute methanol. It was characterized by elemental analyses, IR, tH NMR and X-ray single-crystal diffraction. The compound crystallizes in the wiclinic system, space group PI, with a = 6.4075（11）, b = 10.2821（18）, c = 12.573（2） A, α = 92.606（3）,β= 100.980（3）, γ = 90.994（3）°, V= 812.1（2） A3, Mr = 299.36, Z = 2, F（000） = 320, Dc=1.224 g/cm^3, T= 293（2） K,μ = 0.083 mm^-1 and 2 = 0.71073 A, the final R = 0.0555 and wR = 0.1619 for 2442 observed reflections with I 〉 2σ（I）. The colnpound was valued for its antimicrobial activity against bacterial strands using the agar diffusion method. It is found to be active against Candida albicans and Staphylococcus aureus.
基金
This work was supported by the Key Laboratory of Marine Biotechnology of Jiangsu Province
