新型鼻塞持续气道正压呼吸治疗新生儿呼吸窘迫综合征临床观察

A clinical observation on the treatment of NRDS adopting a new type of CPAP

目的观察新型鼻塞持续气道正压呼吸(CPAP)治疗新生儿呼吸窘迫综合征的疗效。方法将42例新生儿呼吸窘迫综合征(NRDS)分为2组,新型鼻塞CPAP组(nCPAP)26例,采用新型鼻塞CPAP仪(Infant flow CPAP,VIA-SYS Healthcare美国)治疗,水封瓶CPAP组(bCPAP)16例,比较分析2组病例的临床疗效。结果nCPAP组治疗成功率为84.62%(bCPAP组为43.75%),治疗失败率为15.38%(bCPAP组为56.25%),治愈率为76.92%(bCPAP组为37.5%),病死率为3.85%(bCPAP组为18.75%),两组比较差异均有显著意义。结论新型鼻塞CPAP比简易水封瓶CPAP具有疗效好、不良反应少等明显优点。

Objective： To study the effect of the treatment of neonatal respiratory distress syndrome （NRDS） adopting a new type of continuous positive airway pressure （CPAP）. Methods ： 42 cases of NRDS were divided into 2 groups, the group of nCPAP （26） adopted a type Infant flow CPAP （VIASYS Heahhcare, American） ; the group of bCPAP （16） adopted the old -type CPAP, We compare the results of the two groups. Results： The treatment success rate of nCPAP was 84. 62% （bCPAP 43.75% ） ; the treatment failure rate of nCPAP was 15, 38% （bCPAP 56. 25% ） ; the healing rate of nCPAP was 76.92% （bCPAP 36.5% ） ; the fatality rate of nCPAP was 3.85% （bCPAPI8.75%）. There were significant difference between the two groups. Conclusions： There are more advantage and less side effect of the treatment between nCPAP and bCPAP in NRDS.