抗栓酶预防肠粘连的动物实验观察

Experimental study on the prevention of peritoneal adhesion using ahalysantinfarctasum and intralipid

家兔54只,随机分为三组,制成肠粘连模型,分别腹腔放置蝮蛇抗栓酶与脂肪乳剂混合液或右旋糖酐,并以生理盐水作对照,结果显示,蝮蛇抗栓酶与脂肪乳剂混合液具有显著的预防术后腹腔粘连的作用(P<0.01),且较右旋糖酐为佳(P<0.05)。

Fifty -four rabbits which were made as the models of peritoneal adhesion were given peritoneal lavage using a mixture of ahalysantinfarctasum and 10% intralipid or 6% dextran(D40)respectively. and compared with control group. The results showed significant effect of prevention peritoneal adhesion in both group (p<0. 01). The effect of mixture of ahalysantinfarctasum and 10% intralipid is more obvious than that of dextran(p<0. 01). The experimental studies showed that mixture of ahalysantinfarctasum and 10%intralipid played an important role in the prevention of postoperative peritoneal adhesion.