河北省麻疹实验室网络的建立和运转状况分析

Analysis on Measles Laboratory Network Establishment and Running Situation in Hebei Province

目的 评价河北省麻疹实验室网络（MLNW）在加速控制麻疹中的作用。方法 对1999-2004年MLNW检测结果和数据进行分析。结果 河北省1999-2004年麻疹监测系统共报告调查疑似麻疹5474例，MLNW检测血清标本4560份，实验室诊断率平均为83．30％，麻疹IgM抗体阳性率为49．06％，风疹IgM抗体阳性率为35．59％。2003、2004年MLNW接收标本后3d内及时检测率为73．60％（1701／2311）。2000-2004年发放考核标本763份，符合率为97．25％。2001-2004年复核检测标本730份，符合率为95．80％。2001-2004年省疾病预防控制中心（CDC）麻疹实验室接受中国CDC病毒病预防控制所国家麻疹实验室考核和标本复核检测，均为100分。河北省CDC共分离到3株麻疹病毒，均为H1基因型。结论 MLNW的建立和正常运转，在麻疹监测中发挥了重要作用，疑似麻疹病例的实验室诊断率、3d内标本检测率、标本的检测符合率均维持在较高水平，现阶段河北省流行的麻疹野病毒为H1基因型。

Objective The study is to evaluate the effect of measles laboratory network in speeding up measles control. Methods We analyzed the data of the measles laboratory network during 1999 2004. Results From 1999 to 2004, the measles surveillance system reported 5474 suspected measles cases. The measles laboratory network had detected 4 560 cases. The positive rate of the measles IgM antibody is 49.06 %, the rubella IgM antibody is 14.78 %. In 2003 and 2004, when the laboratory network received specimen and detected in three days, the ratio is 73.60% （ 1701/2311 ）. During 2001-2004, the municipal measles laboratory network detected 763 blind sera specimen. The identical rate is 97.25 %. During 2001 -2004, after provincial measles laboratory detected 730 specimen repeatedly, the identical rate is 95.80 %. During 2001- 2004, checked by the national measles laboratory, the provincial laboratory got 100 marks each year. The 3 strains of wild measles virus isolated from Hebei Province are H1 gene type. Conclusion The establishment and running of the measles laboratory network played very important role in measles surveillance system. The rate of the laboratory detected, the ratio of the specimen detected in three days and the rate of identical results are in high level, which improved the diagnosis level and quality of the suspected measles cases. The strains of the epidemic wild measles virus are Hi gene type in the past ten years in Hebei Province. The laboratory of the measles virus isolation need be strengthened and improved.